Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 6/20 | 0.47 |
| ▸ | EDNRB | P24530 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434729 | 0.91 | EDNRA (0.40) | EDNRAALDH1A1TSHRBRS3 | |
| SCHEMBL8434730 | 0.83 | EDNRA (0.39) | EDNRAEDNRBALDH1A1TSHRBRS3 | |
| SCHEMBL7501757 | 0.83 | EDNRA (0.55) | EDNRAEDNRBBRS3 | |
| SCHEMBL7496916 | 0.82 | EDNRA (0.54) | EDNRAEDNRBBRS3 | |
| SCHEMBL7499877 | 0.79 | EDNRA (0.45) | EDNRAEDNRBALDH1A1BRS3 | |
| SCHEMBL7501847 | 0.78 | EDNRA (0.58) | EDNRAALDH1A1 | |
| SCHEMBL7499419 | 0.77 | EDNRA (0.45) | EDNRAEDNRBALDH1A1BRS3 | |
| SCHEMBL8434967 | 0.77 | EDNRA (0.63) | EDNRA | |
| SCHEMBL7506638 | 0.75 | EDNRA (0.45) | EDNRAEDNRBALDH1A1BRS3 | |
| SCHEMBL8435078 | 0.75 | EDNRA (0.47) | EDNRABRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5907006-A | Compositions for the coating of substrates of matt appearance | RENNIE STEPHEN (GB) | 1999-05-25 | — | — | US | claimed |
| EP-0776325-B1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2002-11-20 | — | — | EP | disclosed |
| US-5932741-A | TREATING ILLNESSES RESULTING FROM ABNORMAL STIMULATION OF ENDOTHELIN RECEPTORS | HOECHST MARION ROUSSEL (FR) | 1999-08-03 | — | — | US | disclosed |
| US-5811444-A | IMIDAZOLE DERIVATIVES | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |
| EP-0776325-A1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1997-06-04 | — | — | EP | disclosed |
| WO-1996004276-A1 | NOVEL USE AND NOVEL DERIVATIVES OF IMIDAZOLE, METHOD FOR PREPARING SAME, NOVEL INTERMEDIATES THUS OBTAINED, MEDICINAL APPLICATIONS OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1996-02-15 | — | — | WO | disclosed |