Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441910 | 0.82 | F2 (0.49) | LTA4HF2ESR1 | |
| SCHEMBL7505643 | 0.76 | SMN1; SMN2 (0.47) | LTA4HGAAESR1POLBMEN1 | |
| SCHEMBL7347611 | 0.75 | LTA4H (0.42) | LTA4HGAAF2ESR1SIGMAR1 | |
| SCHEMBL7349365 | 0.75 | F2 (0.42) | F2MEN1KMT2A | |
| SCHEMBL6963429 | 0.73 | LTA4H (0.56) | LTA4HSIGMAR1MEN1KMT2A | |
| SCHEMBL7441879 | 0.73 | TDP1 (0.52) | ESR1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL7348255 | 0.72 | KDM4E (0.41) | LTA4HGAAF2POLBSIGMAR1 | |
| SCHEMBL1427541 | 0.72 | GAA (0.61) | GAAPOLBMEN1KMT2ATDP1 | |
| SCHEMBL7346857 | 0.72 | PSMB1 (0.48) | LTA4HESR1 | |
| SCHEMBL7347810 | 0.72 | HTT (0.49) | LTA4HPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |