Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441879 | 0.83 | TDP1 (0.52) | SMN1; SMN2TDP1MEN1KMT2AKDM4E | |
| SCHEMBL7108553 | 0.81 | KDM4E (0.49) | POLBKDM4EESR1ESR2LTA4H | |
| SCHEMBL7650467 | 0.78 | KDM4E (0.57) | KDM4EESR1ESR2LTA4HALDH1A1 | |
| SCHEMBL7501980 | 0.76 | LTA4H (0.45) | SMN1; SMN2TDP1MEN1KMT2APOLB | |
| SCHEMBL7451698 | 0.75 | POLB (0.58) | SMN1; SMN2TDP1MEN1KMT2APOLB | |
| SCHEMBL7777295 | 0.73 | LTA4H (0.53) | ESR1ESR2LTA4H | |
| SCHEMBL27949662 | 0.72 | CYP3A4 (0.46) | SMN1; SMN2TDP1ESR1ESR2 | |
| SCHEMBL3130426 | 0.72 | LTA4H (0.52) | ESR1ESR2LTA4H | |
| SCHEMBL7443798 | 0.71 | PSMB1 (0.50) | KDM4EESR1ESR2LTA4H | |
| SCHEMBL6962494 | 0.68 | LTA4H (0.57) | SMN1; SMN2KMT2APOLBKDM4ELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |