Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505643 | 0.83 | SMN1; SMN2 (0.47) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL7108553 | 0.76 | KDM4E (0.49) | KDM4EESR1ESR2 | |
| SCHEMBL7650467 | 0.75 | KDM4E (0.57) | KDM4EESR1ESR2ALDH1A1 | |
| SCHEMBL7501980 | 0.73 | LTA4H (0.45) | TDP1SMN1; SMN2MEN1KMT2AESR1 | |
| SCHEMBL7443798 | 0.73 | PSMB1 (0.50) | KDM4EESR1ESR2 | |
| SCHEMBL7777295 | 0.72 | LTA4H (0.53) | ESR1ESR2 | |
| SCHEMBL3130426 | 0.71 | LTA4H (0.52) | ESR1ESR2 | |
| SCHEMBL14453571 | 0.70 | SMN1; SMN2 (0.97) | TDP1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL1927451 | 0.70 | ESR1 (0.56) | SMN1; SMN2MEN1KMT2AKDM4EESR1 | |
| SCHEMBL8264564 | 0.69 | TDP1 (1.00) | TDP1SMN1; SMN2KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |