Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572668 | 0.90 | KMT2A (0.50) | KMT2AL3MBTL1LMNAESR1USP2 | |
| SCHEMBL8798493 | 0.86 | USP2 (0.52) | KMT2AL3MBTL1USP2NPC1RAB9A | |
| SCHEMBL8801750 | 0.85 | USP2 (0.47) | KMT2AL3MBTL1LMNAAVPR2USP2 | |
| SCHEMBL7493834 | 0.84 | KMT2A (0.65) | KMT2AL3MBTL1NPC1RAB9ASORT1 | |
| SCHEMBL7505880 | 0.81 | SGMS2 (0.45) | KMT2AL3MBTL1LMNAESR1NPC1 | |
| SCHEMBL7502174 | 0.80 | L3MBTL1 (0.49) | KMT2AL3MBTL1USP2NPC1RAB9A | |
| SCHEMBL8815552 | 0.76 | NPC1 (0.57) | KMT2AL3MBTL1LMNANPC1RAB9A | |
| SCHEMBL8797556 | 0.76 | CYP11B2 (0.58) | KMT2AL3MBTL1LMNAUSP2NPC1 | |
| SCHEMBL8798613 | 0.76 | DHODH (0.54) | KMT2ALMNAUSP2RAB9ASORT1 | |
| SCHEMBL7501376 | 0.75 | KMT2A (0.63) | KMT2AL3MBTL1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-A1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-12-10 | — | — | EP | disclosed |