Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499602 | 0.95 | MAPT (0.44) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL7495533 | 0.76 | GRM2 (0.40) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL3880710 | 0.74 | CYP19A1 (0.44) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL7499826 | 0.73 | NPC1 (0.46) | ALDH1A1MAPTDDB1CRBNNPC1 | |
| SCHEMBL7498016 | 0.73 | MEN1 (0.46) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL145755 | 0.73 | NOS1 (0.50) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL30074503 | 0.73 | NOS1 (0.50) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL13867519 | 0.68 | NOS1 (0.32) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL9559207 | 0.67 | NOS1 (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL7503685 | 0.64 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757681-B1 | CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-09-18 | — | — | EP | disclosed |
| WO-1995029900-A1 | CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |