Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507764 | 0.90 | TRPV4 (0.34) | TRPV4CYP2A6RORCCYP11B2BRPF1 | |
| SCHEMBL7220183 | 0.76 | CYP11B2 (0.43) | CCR9CYP2A6RORCCYP11B2CYP19A1 | |
| SCHEMBL7507457 | 0.71 | CDC7 (0.39) | TRPV4CYP2A6CDC7CDK2 | |
| SCHEMBL23458895 | 0.70 | BRPF1 (0.39) | CCR9RORCCYP11B2BRPF1CYP11B1 | |
| SCHEMBL29965268 | 0.70 | BRPF1 (0.39) | CCR9RORCCYP11B2BRPF1CYP11B1 | |
| SCHEMBL16168681 | 0.67 | CYP2A6 (0.47) | CCR9CYP2A6CYP11B2CYP19A1BRPF1 | |
| SCHEMBL7491601 | 0.65 | CYP11B2 (0.46) | CCR9CYP2A6CYP11B2CYP19A1BRPF1 | |
| SCHEMBL7435149 | 0.65 | ACSS2 (0.44) | CCR9CYP2A6RORCCYP11B2CYP19A1 | |
| SCHEMBL27401589 | 0.65 | PPARG (0.43) | CCR9CYP2A6CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL7495800 | 0.65 | ACSS2 (0.41) | CCR9CYP2A6CYP11B2CYP19A1BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222167-A2 | METHOD FOR PRODUCING INDOLE DERIVATIVES ON A SOLID PHASE | MERCK PATENT GmbH (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001023353-A2 | METHOD FOR PRODUCING INDOLE DERIVATIVES ON A SOLID PHASE | MERCK PATENT GMBH (DE) | 2001-04-05 | — | — | WO | disclosed |