Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LIPC | P11150 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507907 | 0.92 | RAB9A (0.48) | RAB9AMIFHDAC6NPC1SMN1; SMN2 | |
| SCHEMBL7504359 | 0.88 | QDPR (0.46) | NAMPTRAB9AMIFHDAC6NPC1 | |
| SCHEMBL7505583 | 0.88 | RAB9A (0.45) | RAB9AMIFHDAC6NPC1SMN1; SMN2 | |
| SCHEMBL7501060 | 0.86 | RAB9A (0.43) | NAMPTRAB9AMIFMEN1KMT2A | |
| SCHEMBL7501044 | 0.86 | RAB9A (0.43) | NAMPTRAB9AMIFMEN1KMT2A | |
| SCHEMBL7514922 | 0.79 | NAMPT (0.48) | NAMPTCDK7CDK13CDK12GRM1 | |
| SCHEMBL6397227 | 0.79 | MAOA (0.49) | NAMPTPDK4 | |
| SCHEMBL6397236 | 0.79 | MAOA (0.49) | NAMPTPDK4 | |
| SCHEMBL10189855 | 0.79 | RAB9A (0.45) | RAB9AMIFMEN1KMT2AHDAC6 | |
| SCHEMBL7508392 | 0.79 | RAB9A (0.43) | RAB9AMIFHDAC6NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920421-B1 | ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-11-06 | — | — | EP | claimed |