SCHEMBL750561

SCHEMBL750561

CCOCCN(CCOCC)C(=O)c1cccc(SC)c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.44
HPGD P15428 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 5/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
BACE1 P56817 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
ALOX15 P16050 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28959047 0.84 TP53 (0.49) HPGDTDP1LMNASMN1; SMN2RAB9A
SCHEMBL749799 0.83 NAMPT (0.50) NAMPTHPGDLMNASMN1; SMN2RAB9A
SCHEMBL29410885 0.79 NAMPT (0.57) NAMPTHPGDLMNAALDH1A1TP53
SCHEMBL750583 0.77 ALDH1A1 (0.43) NAMPTHPGDTDP1LMNASMN1; SMN2
SCHEMBL13557494 0.74 NAMPT (0.46) NAMPTHPGDLMNASMN1; SMN2RAB9A
SCHEMBL751001 0.72 TP53 (0.49) NAMPTHPGDLMNASMN1; SMN2RAB9A
SCHEMBL14549899 0.72 NAMPT (0.53) NAMPTHPGDTDP1LMNASMN1; SMN2
SCHEMBL751003 0.71 NAMPT (0.47) NAMPTLMNASMN1; SMN2RAB9ANPC1
SCHEMBL12195077 0.71 NAMPT (0.47) NAMPTHPGDLMNASMN1; SMN2RAB9A
SCHEMBL14549871 0.71 NAMPT (0.41) NAMPTHPGDLMNASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293436-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-8293436-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-8137890-B2 Colored photosensitive composition, color filter, and method for manufacturing color filter FUJIFILM CORPORATION (JP) 2012-03-20 US disclosed
US-8137890-B2 Colored photosensitive composition, color filter, and method for manufacturing color filter FUJIFILM CORPORATION (JP) 2012-03-20 US disclosed
US-7914956-B2 Dye-containing negative working curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2011-03-29 US disclosed
US-7914956-B2 Dye-containing negative working curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2011-03-29 US disclosed
US-7910272-B2 Dye-containing photosensitive composition, color filter using the same, and production method thereof FUJIFILM CORPORATION (JP) 2011-03-22 US disclosed
US-7910272-B2 Dye-containing photosensitive composition, color filter using the same, and production method thereof FUJIFILM CORPORATION (JP) 2011-03-22 US disclosed
US-7842440-B2 Colored curable composition, color filter and manufacturing method thereof FUJIFILM CORPORATION (JP) 2010-11-30 US disclosed
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 US disclosed
US-20070212623-A1 Dye-containing negative working curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070212623-A1 Dye-containing negative working curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070203255-A1 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed
US-20070203255-A1 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed
US-20070190435-A1 Dye-containing photosensitive composition, color filter using the same, and production method thereof FUJIFILM CORPORATION (JP) 2007-08-16 US disclosed
US-20070190435-A1 Dye-containing photosensitive composition, color filter using the same, and production method thereof FUJIFILM CORPORATION (JP) 2007-08-16 US disclosed
US-20070099096-A1 Dye-containing curable composition, color filter and method of producing thereof FUJIFILM CORPORATION 2007-05-03 US disclosed
US-20070099096-A1 Dye-containing curable composition, color filter and method of producing thereof FUJIFILM CORPORATION 2007-05-03 US disclosed
US-20070072096-A1 Negative curable dye-containing composition, color filter, and method of manufacturing the same FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070072096-A1 Negative curable dye-containing composition, color filter, and method of manufacturing the same FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME PPOX, CYBA, HBB NAMPT 1382/4885HPGD 131/4885TDP1 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.