Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 8/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205979 | 0.89 | ALDH1A1 (0.38) | PLAT | |
| SCHEMBL2708748 | 0.89 | ALDH1A1 (0.38) | PLAT | |
| SCHEMBL18462699 | 0.89 | ALDH1A1 (0.38) | PLAT | |
| SCHEMBL934406 | 0.82 | DGAT1 (0.32) | DGAT1PRCP | |
| SCHEMBL934404 | 0.82 | DGAT1 (0.32) | DGAT1PRCP | |
| SCHEMBL933196 | 0.82 | MAPT (0.32) | DGAT1PRCP | |
| SCHEMBL933195 | 0.82 | MAPT (0.32) | DGAT1PRCP | |
| SCHEMBL9977254 | 0.81 | CHRNB2 (0.32) | PLATDGAT1 | |
| SCHEMBL749358 | 0.81 | DGAT1 (0.33) | DGAT1PRCP | |
| SCHEMBL27978679 | 0.80 | TP53 (0.31) | DGAT1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016971-B | Antiviral compound | PHARMASSET INC. (US) | 2016-05-25 | — | — | CN | disclosed |
| CN-103977406-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-08-13 | — | — | CN | disclosed |
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |