Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 12/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507329 | 0.90 | P2RY2 (0.41) | P2RY2 | |
| SCHEMBL7509787 | 0.81 | P2RY2 (0.70) | P2RY2 | |
| SCHEMBL7505694 | 0.80 | P2RY2 (0.39) | P2RY2 | |
| SCHEMBL7495877 | 0.80 | P2RY2 (0.46) | P2RY2MAPT | |
| SCHEMBL7485651 | 0.79 | P2RY2 (0.47) | P2RY2MAPTRXFP1 | |
| SCHEMBL7512427 | 0.73 | MAPK14 (0.33) | P2RY2 | |
| SCHEMBL7504709 | 0.71 | P2RY2 (0.39) | P2RY2 | |
| SCHEMBL7503428 | 0.71 | P2RY2 (0.86) | P2RY2 | |
| SCHEMBL7500497 | 0.71 | P2RY2 (0.62) | P2RY2 | |
| SCHEMBL7505786 | 0.69 | GRM7 (0.35) | P2RY2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042320-B1 | NEW COMPOUNDS WHICH ARE P2-PURINOCEPTOR 7-TRANSMEMBRANE (TM) G-PROTEIN COUPLED RECEPTOR ANTAGONISTS | ASTRAZENECA UK LTD (GB) | 2002-02-13 | — | — | EP | claimed |
| US-6218376-B1 | FOR TREATING INFLAMMATORY DISEASES | ASTRAZENECA UK LIMITED (GB) | 2001-04-17 | — | — | US | claimed |
| EP-1042320-B1 | NEW COMPOUNDS WHICH ARE P2-PURINOCEPTOR 7-TRANSMEMBRANE (TM) G-PROTEIN COUPLED RECEPTOR ANTAGONISTS | ASTRAZENECA UK LTD (GB) | 2002-02-13 | — | — | EP | disclosed |
| US-6218376-B1 | FOR TREATING INFLAMMATORY DISEASES | ASTRAZENECA UK LIMITED (GB) | 2001-04-17 | — | — | US | disclosed |