Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL675736 | 0.72 | — | — | |
| SCHEMBL7510360 | 0.68 | GPR3 (0.50) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL4880315 | 0.67 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL395593 | 0.65 | GPR3 (0.42) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL4873948 | 0.63 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| Hydrochloric Acid SCHEMBL4872846 | 0.63 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL7629468 | 0.62 | GPR3 (0.32) | GPR3 | |
| SCHEMBL7630742 | 0.62 | GPR3 (0.39) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL673077 | 0.62 | GPR3 (0.35) | GPR3SLC22A2SLC22A3 | |
| SCHEMBL7034053 | 0.61 | GPR3 (0.44) | GPR3SLC22A2SLC22A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648946-B1 | OLEFIN POLYMERIZATION PROCESS | BASELL POLYOLEFINE GMBH (DE) | 2015-07-15 | — | — | EP | disclosed |
| US-8058350-B2 | Polypropylene composition | Basell Poliolefine Italia, s.r.l. (IT) | 2011-11-15 | — | — | US | disclosed |
| EP-1680468-B1 | POLYPROPYLENE COMPOSITION | BASELL POLIOLEFINE SRL (IT) | 2011-08-17 | — | — | EP | disclosed |
| US-20080160862-A1 | Polyolefin Composition, Fibres and Nonwoven Fabrics | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2008-07-03 | — | — | US | disclosed |
| US-20070078224-A1 | Polypropylene composition | BASELL POLIOEFINE ITALIA S.R.L. (IT) | 2007-04-05 | — | — | US | disclosed |
| US-7122606-B2 | Olefin polymerization process | BASELL POLYOLEFINE GMBH (DE) | 2006-10-17 | — | — | US | disclosed |
| US-20060160962-A1 | Olefin polymerization process | BASELL POLYOLEFINE GMBH (DE) | 2006-07-20 | — | — | US | disclosed |