SCHEMBL4375149

SCHEMBL4375149

Cc1cc2c(n1C)C(N([SiH](C)C)C(C)(C)C)c1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.36
SLC22A2 O15244 1/20 0.31
SLC22A3 O75751 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7510360 0.80 GPR3 (0.50) GPR3SLC22A2SLC22A3
SCHEMBL7630742 0.73 GPR3 (0.39) GPR3SLC22A2SLC22A3
SCHEMBL4373543 0.70 ALDH1A1 (0.44)
Hydrochloric Acid SCHEMBL7120044 0.67 GPR3 (0.34) GPR3
SCHEMBL7120789 0.67 GPR3 (0.34) GPR3
SCHEMBL4373398 0.67 ALDH1A1 (0.35)
SCHEMBL7629468 0.64 GPR3 (0.32) GPR3
Hydrochloric Acid SCHEMBL7124364 0.64 GPR3 (0.32) GPR3
Hydrochloric Acid SCHEMBL4880315 0.59 GPR3 (0.44) GPR3SLC22A2SLC22A3
Hydrochloric Acid SCHEMBL4873948 0.59 GPR3 (0.44) GPR3SLC22A2SLC22A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1533324-B1 A ligand for a metallocene catalyst used to prepare propylene based polymers, and its preparation method BASELL POLYOLEFINE GMBH (DE) 2009-05-06 EP disclosed
EP-1533324-A2 A ligand for a metallocene catalyst used to prepare propylene based polymers, and its preparation method Basell Polyolefine GmbH (DE) 2005-05-25 EP disclosed
EP-1159310-B1 PROCESS FOR PRODUCING SUBSTANTIALLY AMORPHOUS PROPYLENE-BASED POLYMERS BASELL POLYOLEFINE GMBH (DE) 2005-03-30 EP disclosed
US-6730754-B2 COORDINATION POLYMERIZATION CATALYST BASELL POLYOLEFINE GMBH (DE) 2004-05-04 US disclosed
US-20020147286-A1 Process for producing substantially amorphous propylene-based polymers EQUISTAR CHEMICALS, LP 2002-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020147286-A1 Process for producing substantially amorphous propylene-based polymers GRB7, CHRM1, CPNE4 GPR3 1504/4885SLC22A2 4252/4885SLC22A3 4597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.