Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879464 | 0.87 | AGTR1 (0.50) | AGTR1AGTR2PPARG | |
| SCHEMBL8879468 | 0.84 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL9157099 | 0.82 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9153317 | 0.81 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9842316 | 0.81 | AGTR1 (0.60) | AGTR1AGTR2 | |
| SCHEMBL9151336 | 0.79 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL7521287 | 0.78 | MMP3 (0.40) | AGTR1AGTR2PPARG | |
| SCHEMBL9148754 | 0.78 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8879806 | 0.78 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8979891 | 0.76 | AGTR1 (0.59) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556080-B1 | Bicyclic pyridine derivatives, process for their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | AVENTIS PHARMA SA (FR) | 2002-05-08 | — | — | EP | claimed |
| US-5420138-A | Antivasoconstriction compounds and cardiovascular disorders | ROUSSEL-UCLAF (FR) | 1995-05-30 | — | — | US | claimed |
| EP-0556080-B1 | Bicyclic pyridine derivatives, process for their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | AVENTIS PHARMA SA (FR) | 2002-05-08 | — | — | EP | disclosed |
| US-5650414-A | PYRAZOLOPYRIDINES OR IMIDAZOLOPYRIDINES | ROUSSEL UCLAF (FR) | 1997-07-22 | — | — | US | disclosed |
| US-5420138-A | Antivasoconstriction compounds and cardiovascular disorders | ROUSSEL-UCLAF (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0556080-A1 | Bicyclic pyridine derivatives, process for their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1993-08-18 | — | — | EP | disclosed |