SCHEMBL7511345

SCHEMBL7511345

CC(C)(C)c1c(OC(=O)O)ccc(I)c1I

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL399301 0.71 PTGDR2 (0.35)
SCHEMBL7650978 0.70 CYP1A2 (0.38) ATMTDP1
SCHEMBL247427 0.70 TDP1 (0.47) ATMTDP1
SCHEMBL8528375 0.70 ALDH1A1 (0.46)
SCHEMBL16239995 0.69 LMNA (0.34) ATMTDP1
SCHEMBL6233314 0.69 MAPT (0.41) TDP1
SCHEMBL27199180 0.69 PTGDR2 (0.39) ATMTDP1
SCHEMBL7866369 0.68 FABP7 (0.39) TDP1
SCHEMBL6232095 0.68 LMNA (0.33) TDP1
SCHEMBL6234126 0.68 PTGDR2 (0.38) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020177684-A1 Process for producing polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed