Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | PON1 | P27169 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988102 | 0.84 | BACE1 (0.38) | BACE1ALOX15ALOX12COMTACHE | |
| SCHEMBL5465470 | 0.83 | ESR1 (0.42) | ALOX15CA12CA9MEN1KMT2A | |
| SCHEMBL27688204 | 0.80 | PIK3CA (0.38) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL2196851 | 0.79 | BCL2L1 (0.54) | BACE1ALOX15ALOX12MEN1KMT2A | |
| SCHEMBL5465416 | 0.76 | APP (0.52) | — | |
| SCHEMBL3544339 | 0.75 | ACHE (0.35) | ACHEMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5899213 | 0.72 | HPGD (0.35) | ALOX15ACHEMEN1KMT2ATDP1 | |
| SCHEMBL29019397 | 0.72 | PTGS2 (0.40) | BACE1ACHEMEN1KMT2ANPC1 | |
| SCHEMBL28325875 | 0.72 | ALDH1A1 (0.36) | ACHENPC1RAB9ATDP1PTGS1 | |
| SCHEMBL14283893 | 0.71 | BACE1 (0.55) | BACE1ALOX15ALOX12COMTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522868-B2 | Tetrakis(ether-substituted formylphenyl) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| US-20160016884-A1 | NEW TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-01-21 | — | — | US | disclosed |
| US-8921613-B2 | Polynuclear poly(phenol) family | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-12-30 | — | — | US | disclosed |
| US-20120277479-A1 | NOVEL POLYNUCLEAR POLY(PHENOL) FAMILY | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-11-01 | — | — | US | disclosed |
| US-20110172457-A1 | TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED FROM THE SAME | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016884-A1 | NEW TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) | AHR, PAH, ALK | BACE1 4202/4885ALOX15 1023/4885ALOX12 724/4885 |
| US-20120277479-A1 | NOVEL POLYNUCLEAR POLY(PHENOL) FAMILY | PAH, C1S, AP1S1 | BACE1 4488/4885ALOX15 2933/4885ALOX12 2578/4885 |
| US-20110172457-A1 | TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED FROM THE SAME | AHR, PAH, ARNT | BACE1 4702/4885ALOX15 1456/4885ALOX12 973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.