Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515349 | 0.91 | CAPN1 (0.61) | CAPN1CTSKCTSSCTSL | |
| SCHEMBL7517799 | 0.88 | BMP1 (0.47) | BMP1CAPN1CTSKCTSBCTSS | |
| SCHEMBL8812581 | 0.87 | CTSK (0.60) | CAPN1CTSKCTSBCTSSCTSL | |
| SCHEMBL8812573 | 0.87 | CTSK (0.60) | CAPN1CTSKCTSBCTSSCTSL | |
| SCHEMBL7511787 | 0.80 | CAPN1 (0.44) | CAPN1CTSKCTSBCTSSCTSL | |
| SCHEMBL7512998 | 0.80 | CAPN1 (0.53) | BMP1CAPN1CTSKCTSBCTSS | |
| SCHEMBL8810216 | 0.77 | CTSL (0.58) | CAPN1CTSKCTSBCTSSKLK7 | |
| SCHEMBL8810223 | 0.77 | CTSL (0.58) | CAPN1CTSKCTSBCTSSKLK7 | |
| SCHEMBL8404288 | 0.77 | CAPN1 (0.68) | CAPN1CTSKCTSBCTSSCTSL | |
| SCHEMBL8808396 | 0.77 | CTSK (0.54) | CAPN1CTSKCTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | claimed |
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | disclosed |