SCHEMBL751194

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12206702	0.87	NPSR1 (0.46)	NPSR1NPC1RAB9ATP53HPGD
	SCHEMBL749812	0.76	NPSR1 (0.33)	NPSR1HPGDSMN1; SMN2MAPTLMNA
	SCHEMBL751851	0.76	CYP11B1 (0.32)	NPSR1HPGDSMN1; SMN2MAPTLMNA
	SCHEMBL752070	0.75	SMN1; SMN2 (0.43)	NPSR1NPC1RAB9AHPGDSMN1; SMN2
	SCHEMBL754375	0.75	FYN (0.33)	NPSR1SMN1; SMN2
	SCHEMBL2779143	0.74	NPSR1 (0.39)	NPSR1NPC1RAB9ATP53HPGD
	SCHEMBL754752	0.72	USP1 (0.36)	SMN1; SMN2MAPTPOLBKMT2A
	SCHEMBL752754	0.71	NPSR1 (0.35)	NPSR1TP53MAPTTHRBRIPK1
	SCHEMBL752004	0.70	ALDH1A1 (0.40)	NPSR1HPGDMAPTPOLBTSHR
	SCHEMBL754533	0.70	SMN1; SMN2 (0.34)	NPSR1NPC1RAB9AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.