Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749567 | 0.84 | HPGD (0.46) | HPGDKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL5855074 | 0.73 | TAAR1 (0.50) | HPGDKDM4ECYP1A2ALDH1A1GAA | |
| SCHEMBL31643340 | 0.71 | CYP1A2 (0.60) | HPGDKDM4EMAPTCYP1A2ALDH1A1 | |
| SCHEMBL12433153 | 0.71 | CYP1A2 (0.60) | HPGDKDM4EMAPTCYP1A2ALDH1A1 | |
| SCHEMBL27864959 | 0.69 | KDM4E (0.40) | HPGDKDM4EMAPTCYP1A2ALDH1A1 | |
| SCHEMBL23232393 | 0.68 | CYP2C19 (0.61) | HPGDKDM4ECYP1A2ALDH1A1KMT2A | |
| SCHEMBL12433151 | 0.67 | HPGD (0.55) | HPGDKDM4EMAPTCYP1A2ALDH1A1 | |
| SCHEMBL31643367 | 0.66 | HPGD (0.54) | HPGDKDM4EMAPTCYP1A2ALDH1A1 | |
| SCHEMBL398923 | 0.66 | KDM4E (0.61) | KDM4EMAPTCYP1A2ALDH1A1KMT2A | |
| SCHEMBL20144313 | 0.66 | KDM4E (0.58) | KDM4EMAPTCYP1A2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102421783-B | Herbicidal compounds | SYNGENTA LTD | 2014-08-06 | — | — | CN | disclosed |
| US-8569301-B2 | 6, 6-dioxo-6-thia-1, 4-diaza-naphthalenes as herbicides | SYNGENTA LIMITED (GB) | 2013-10-29 | — | — | US | disclosed |
| EP-2430028-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
| CN-102421783-A | Herbicidal compounds | SYNGENTA LTD | 2012-04-18 | — | — | CN | disclosed |
| EP-2430028-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010130970-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115726-A1 | HERBICIDAL COMPOUNDS | DDT, NAT1, DDAH1 | HPGD 438/4885KDM4E 2464/4885MAPT 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.