SCHEMBL749567

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL751200	0.84	HPGD (0.42)	HPGDKDM4EL3MBTL1GAATSHR
	SCHEMBL12433169	0.72	HPGD (0.58)	HPGDKDM4EL3MBTL1GAAPOLB
	SCHEMBL30714096	0.72	HPGD (0.58)	HPGDKDM4EL3MBTL1GAAPOLB
	SCHEMBL27847857	0.72	ABL1 (0.38)	HPGDKDM4EL3MBTL1ABL1SRC
	SCHEMBL18191250	0.71	L3MBTL1 (0.43)	KDM4EL3MBTL1GAATSHRALDH1A1
	SCHEMBL270666	0.71	ABL1 (0.38)	HPGDKDM4EL3MBTL1ABL1SRC
	SCHEMBL394073	0.70	L3MBTL1 (0.60)	KDM4EL3MBTL1GAAPOLBTSHR
	SCHEMBL749664	0.70	L3MBTL1 (0.44)	KDM4EL3MBTL1GAAPOLBTDP1
	SCHEMBL9957265	0.69	L3MBTL1 (0.46)	KDM4EL3MBTL1ABL1SRCTDP1
	SCHEMBL753438	0.69	ALDH1A1 (0.38)	HPGDKDM4EL3MBTL1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.