Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956279 | 0.81 | SLC6A3 (0.58) | SLC6A3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL7828011 | 0.81 | SLC6A3 (0.58) | SLC6A3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL961019 | 0.81 | SLC6A3 (0.57) | SLC6A3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL27302896 | 0.81 | SLC6A3 (0.54) | SLC6A3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL7236223 | 0.80 | SLC6A3 (0.59) | SLC6A3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL13124077 | 0.79 | SLC6A3 (0.58) | SLC6A3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL959762 | 0.79 | SLC6A3 (0.58) | SLC6A3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL17892330 | 0.79 | SLC6A3 (0.55) | SLC6A3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL4246228 | 0.77 | CHRM2 (0.60) | SLC6A3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL961750 | 0.77 | SLC6A3 (0.53) | SLC6A3CHRM2CHRM1CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395762-B1 | METABOLISM DISEASES; HYPOGLYCEMIC AGENTS; ANTICHOLESTEROL AGENTS; ANTIDIABETIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION | 2002-05-28 | — | — | US | disclosed |
| US-20020025973-A1 | Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-02-28 | — | — | US | disclosed |
| WO-2002006210-A1 | PHENYL AMINO SQUARATE AND THIADIAZOLE DIOXIDE BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020025973-A1 | Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | SLC6A3 207/4885CHRM2 1740/4885CHRM1 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.