Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520689 | 0.86 | TSHR (0.39) | S1PR3TSHRLMNAHTTKCNH2 | |
| SCHEMBL6847398 | 0.85 | PLA2G2A (0.39) | S1PR3PLA2G2ATSHRCA12CA1 | |
| SCHEMBL92103 | 0.82 | PLA2G2A (0.50) | PLA2G2ATSHRALDH1A1 | |
| SCHEMBL8059417 | 0.81 | LMNA (0.41) | S1PR3TSHRLMNAHTTKCNH2 | |
| SCHEMBL6848210 | 0.80 | CA2 (0.42) | TSHRLMNAHTTKCNH2CYP2D6 | |
| SCHEMBL12535684 | 0.77 | PLA2G2A (0.45) | PLA2G2ATSHR | |
| SCHEMBL12083487 | 0.77 | PLA2G2A (0.39) | PLA2G2ATSHRLMNANR1I2ALDH1A1 | |
| SCHEMBL92094 | 0.76 | PLA2G2A (0.41) | PLA2G2ATSHRKCNH2CYP2D6CYP2C9 | |
| SCHEMBL15372495 | 0.74 | PLA2G2A (0.41) | PLA2G2ATSHRALDH1A1 | |
| SCHEMBL10950170 | 0.74 | TSHR (0.62) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0899614-B1 | Image recording material | FUJI PHOTO FILM CO LTD (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-6162574-A | Image recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-0899614-A1 | Image recording material | Fuji Photo Film Co., Ltd. (JP) | 1999-03-03 | — | — | EP | disclosed |