Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520689 | 0.86 | TSHR (0.39) | LMNATSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8059419 | 0.86 | MAPT (0.42) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL4741613 | 0.84 | LMNA (0.50) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL3312542 | 0.84 | LMNA (0.50) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL7513550 | 0.81 | S1PR3 (0.40) | LMNANR1I2TSHRCYP2D6CYP2C9 | |
| SCHEMBL8051743 | 0.78 | S1PR3 (0.40) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL3132636 | 0.73 | GAA (0.40) | LMNAMAPTMEN1CYP3A4KMT2A | |
| SCHEMBL9760787 | 0.72 | LMNA (0.41) | LMNATSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9418021 | 0.72 | ALDH1A1 (0.46) | TSHRALDH1A1TP53 | |
| SCHEMBL4605693 | 0.72 | ALDH1A1 (0.46) | TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162574-A | Image recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-12-19 | — | — | US | disclosed |