Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 8/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516093 | 0.90 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14MAPK1 | |
| SCHEMBL7518627 | 0.88 | SMN1; SMN2 (0.40) | MAPK13MAPK12MAPK11MAPK14RAB9A | |
| SCHEMBL7514848 | 0.83 | MAPK14 (0.54) | MAPK13MAPK12MAPK11MAPK14PPARG | |
| SCHEMBL7035322 | 0.77 | MAPK13 (0.38) | MAPK13MAPK12MAPK11MAPK14MAPK1 | |
| SCHEMBL7030642 | 0.75 | KDM4C (0.44) | MAPK13MAPK12MAPK11MAPK14PPARG | |
| SCHEMBL7509072 | 0.73 | MAPK14 (0.53) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL7510773 | 0.73 | MAPK14 (0.68) | MAPK13MAPK12MAPK11MAPK14LMNA | |
| SCHEMBL7513578 | 0.72 | MAPK14 (0.41) | MAPK13MAPK12MAPK11MAPK14PPARG | |
| SCHEMBL7514380 | 0.71 | MAPK13 (0.48) | MAPK13MAPK12MAPK11MAPK14MAPK1 | |
| SCHEMBL7596971 | 0.71 | CMA1 (0.40) | MAPK13MAPK12MAPK11MAPK14RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432962-B2 | Benzophenones as inhibitors of IL-1β and TNF-α | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2002-08-13 | — | — | US | claimed |
| US-20020016347-A1 | Benzophenones as inhibitors of IL-1beta and TNF-alpha | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2002-02-07 | — | — | US | claimed |
| US-6432962-B2 | Benzophenones as inhibitors of IL-1β and TNF-α | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2002-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016347-A1 | Benzophenones as inhibitors of IL-1beta and TNF-alpha | IL1B, IL1A, NFKBIA | MAPK13 1908/4885MAPK12 1184/4885MAPK11 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.