Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26131423 | 1.00 | LMNA (0.37) | LMNACYP2D6ALDH1A1KIF11CYP2C19 | |
| SCHEMBL7523023 | 0.84 | LMNA (0.34) | LMNAALDH1A1KIF11GRIN1GRIN2A | |
| SCHEMBL5503987 | 0.77 | ALDH1A1 (0.35) | LMNACYP2D6ALDH1A1KIF11CYP2C19 | |
| SCHEMBL993539 | 0.77 | ALDH1A1 (0.35) | LMNACYP2D6ALDH1A1KIF11CYP2C19 | |
| SCHEMBL9564566 | 0.73 | KIF11 (0.47) | KIF11KCNH2 | |
| SCHEMBL19859361 | 0.71 | RCE1 (0.44) | LMNAALDH1A1KDM4ERCE1TSHR | |
| SCHEMBL9381848 | 0.71 | RCE1 (0.44) | LMNAALDH1A1KDM4ERCE1TSHR | |
| SCHEMBL6749203 | 0.70 | KIF11 (0.53) | LMNACYP2D6ALDH1A1KIF11CYP2C19 | |
| SCHEMBL4533570 | 0.70 | KIF11 (0.53) | LMNACYP2D6ALDH1A1KIF11CYP2C19 | |
| SCHEMBL5899878 | 0.70 | KIF11 (0.53) | LMNACYP2D6ALDH1A1KIF11CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173397-A1 | STEREOSPECIFIC METHOD FOR PREPARING 4-HYDOXYALK-1-ENE COMPOUNDS | PPG-Sipsy S.C.A. (FR) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066519-A1 | STEREOSPECIFIC METHOD FOR PREPARING 4-HYDOXYALK-1-ENE COMPOUNDS | PPG-SIPSY S.C.A. (FR) | 2000-11-09 | — | — | WO | disclosed |