Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514202 | 0.84 | LMNA (0.37) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL26131423 | 0.84 | LMNA (0.37) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL5775911 | 0.73 | HTT (0.40) | LMNAALDH1A1GAAPKMTRPA1 | |
| SCHEMBL4771137 | 0.71 | TK1 (0.48) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL21087595 | 0.71 | TK1 (0.48) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL5503987 | 0.71 | ALDH1A1 (0.35) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL993539 | 0.71 | ALDH1A1 (0.35) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL9564566 | 0.71 | KIF11 (0.47) | KIF11KCNN4 | |
| SCHEMBL5771311 | 0.69 | HTR2A (0.56) | LMNA | |
| SCHEMBL5773300 | 0.69 | HTR2A (0.56) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173397-A1 | STEREOSPECIFIC METHOD FOR PREPARING 4-HYDOXYALK-1-ENE COMPOUNDS | PPG-Sipsy S.C.A. (FR) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066519-A1 | STEREOSPECIFIC METHOD FOR PREPARING 4-HYDOXYALK-1-ENE COMPOUNDS | PPG-SIPSY S.C.A. (FR) | 2000-11-09 | — | — | WO | disclosed |