Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515600 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7515852 | 0.74 | KMT2A (0.59) | SMN1; SMN2ALDH1A1KMT2AMEN1HCAR3 | |
| SCHEMBL7514525 | 0.73 | KMT2A (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1HCAR3 | |
| SCHEMBL6952927 | 0.72 | ALDH1A1 (0.47) | LTA4HALDH1A1KMT2ALMNASNCA | |
| SCHEMBL6378384 | 0.71 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KMT2ASNCAHCAR3 | |
| SCHEMBL6377823 | 0.71 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KMT2ASNCAHCAR3 | |
| SCHEMBL7598671 | 0.71 | HPGD (0.54) | SMN1; SMN2ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL15862211 | 0.70 | HCAR3 (0.61) | LTA4HALDH1A1LMNAHCAR3 | |
| SCHEMBL992446 | 0.69 | HCAR3 (0.68) | KMT2AMEN1LMNAGAAHCAR3 | |
| SCHEMBL1483517 | 0.69 | CASP6 (0.66) | LMNAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032262-A1 | 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds | ZHANG JINFANG (US) | 2002-03-14 | — | — | US | disclosed |