Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Cymene SCHEMBL7517557 | 1.00 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1L3MBTL1ATM | |
| SCHEMBL3232763 | 0.89 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1L3MBTL1ATM | |
| SCHEMBL7526406 | 0.89 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1L3MBTL1ATM | |
| SCHEMBL7646219 | 0.89 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1L3MBTL1ATM | |
| SCHEMBL7613315 | 0.87 | SLC1A3 (0.55) | SLC1A3SLC1A2SLC1A1L3MBTL1ATM | |
| P-Cymene SCHEMBL3579869 | 0.86 | ALDH1A1 (0.50) | SLC1A3SLC1A2SLC1A1ALDH1A1NPSR1 | |
| P-Cymene SCHEMBL6743208 | 0.86 | NPSR1 (0.47) | SLC1A3SLC1A2SLC1A1ALDH1A1NPSR1 | |
| P-Cymene SCHEMBL7527837 | 0.86 | NPSR1 (0.47) | SLC1A3SLC1A2SLC1A1ALDH1A1NPSR1 | |
| P-Cymene SCHEMBL2240125 | 0.86 | ALDH1A1 (0.50) | SLC1A3SLC1A2SLC1A1ALDH1A1NPSR1 | |
| P-Cymene SCHEMBL3854468 | 0.86 | KEAP1 (0.40) | L3MBTL1ATMALDH1A1NPSR1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495701-B1 | THE PRESENT INVENTION IS DIRECTED TO PROCESSES FOR THE PREPARATION OF A COMPOUND USEFUL FOR TREATING DIABETES, OBESITY, HYPERLIPIDEMIA AND THE LIKE, | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1174426-A1 | METHOD FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES THROUGH AZIDES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-01-23 | — | — | EP | disclosed |