Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 17/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6543281 | 0.99 | OPRM1 (0.54) | OPRM1OPRL1OPRK1 | |
| SCHEMBL4631671 | 0.83 | OPRM1 (0.73) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL7478459 | 0.81 | OPRM1 (0.69) | OPRM1OPRL1OPRK1 | |
| Hydrochloric Acid SCHEMBL7478467 | 0.81 | OPRM1 (0.69) | OPRM1OPRL1OPRK1 | |
| SCHEMBL7309717 | 0.78 | OPRM1 (0.53) | OPRM1OPRL1OPRK1 | |
| SCHEMBL7313869 | 0.78 | OPRM1 (0.56) | OPRM1OPRL1OPRK1 | |
| SCHEMBL7312540 | 0.77 | OPRM1 (0.51) | OPRM1OPRL1OPRK1 | |
| SCHEMBL6544501 | 0.77 | OPRL1 (0.53) | OPRM1OPRL1 | |
| Trifluoroacetic Acid SCHEMBL3404097 | 0.77 | OPRM1 (0.54) | OPRM1OPRL1OPRK1 | |
| SCHEMBL2834926 | 0.76 | OPRM1 (0.72) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241168-A1 | Human NK3 receptor-selective antagonist compounds, process for their obtention and pharmaceutical compositons containing them | SANOFI-SYNTHELABO (FR) | 2002-09-18 | — | — | EP | disclosed |
| EP-1019373-A1 | NOVEL HUMAN NK 3? RECEPTOR-SELECTIVE ANTAGONIST COMPOUNDS, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 2000-07-19 | — | — | EP | disclosed |
| WO-1997010211-A1 | NOVEL HUMAN NK3 RECEPTOR-SELECTIVE ANTAGONIST COMPOUNDS, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1997-03-20 | — | — | WO | disclosed |