SCHEMBL7515001

SCHEMBL7515001

O=C1CCC(C(=O)OC(=O)C2CCC(=O)N2)N1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.48
LMNA P02545 1/20 0.47
TSHR P16473 1/20 0.43
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CNR1 P21554 1/20 0.37
DAGLA Q9Y4D2 1/20 0.37
CNR2 P34972 1/20 0.33
CAD P27708 1/20 0.32
NAMPT P43490 2/20 0.31
TPSAB1 Q15661 1/20 0.31
TPSD1 Q9BZJ3 1/20 0.31
TPSG1 Q9NRR2 1/20 0.31
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7514998 1.00 GAA (0.48) GAALMNATSHRPOLBSMN1; SMN2
SCHEMBL25401240 1.00 GAA (0.48) GAALMNATSHRPOLBSMN1; SMN2
SCHEMBL7720643 0.88 LMNA (0.46) GAALMNATSHRPOLBSMN1; SMN2
SCHEMBL29766719 0.88 LMNA (0.46) GAALMNATSHRPOLBSMN1; SMN2
SCHEMBL6561125 0.85 GAA (0.45) GAALMNATSHRPOLBSMN1; SMN2
SCHEMBL6561121 0.85 GAA (0.45) GAALMNATSHRPOLBSMN1; SMN2
SCHEMBL7752351 0.85 GAA (0.47) GAALMNATSHRPOLBSMN1; SMN2
SCHEMBL6323493 0.83 GAA (0.46) GAALMNATSHRPOLBSMN1; SMN2
SCHEMBL78947 0.83 LMNA (0.48) GAALMNATSHRPOLBSMN1; SMN2
SCHEMBL21628058 0.83 GAA (0.49) GAALMNATSHRPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3693357-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE PYRROLIDONE CARBOXYLIC ACID OR ALKALI METAL SALT THEREOF AJINOMOTO KK (JP) 2024-05-15 EP disclosed
CN-110891934-B Process for producing optically active pyrrolidone carboxylic acid or alkali metal salt thereof 味之素株式会社 2023-12-12 CN disclosed
EP-3693357-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE PYRROLIDONE CARBOXYLIC ACID OR ALKALI METAL SALT THEREOF AJINOMOTO CO., INC. (JP) 2020-08-12 EP disclosed
CN-110891934-A Process for producing optically active pyrrolidone carboxylic acid or alkali metal salt thereof 味之素株式会社 2020-03-17 CN disclosed
US-20020072601-A1 Method for forming amino acid derivatives from tricyclic diketopiperazines UNIVERSITY OF SOUTHERN MISSISSIPPI 2002-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072601-A1 Method for forming amino acid derivatives from tricyclic diketopiperazines AADAT, GLUL, ASNS GAA 2288/4885LMNA 1763/4885TSHR 2774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.