SCHEMBL7515119

SCHEMBL7515119

CON1C(=O)C2C=CCCC2C1=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8130067 0.82
SCHEMBL7511512 0.82 CASP3 (0.34) ALDH1A1THRB
SCHEMBL11709211 0.73 ALDH1A1 (0.30) ALDH1A1
SCHEMBL3728142 0.73 ALDH1A1 (0.38) ALDH1A1
SCHEMBL5711727 0.73 ALDH1A1 (0.30) ALDH1A1
SCHEMBL11609744 0.71
SCHEMBL8149050 0.70 CYP2D6 (0.30)
SCHEMBL10625294 0.69
SCHEMBL10967255 0.69 ALDH1A1 (0.31) ALDH1A1
SCHEMBL5448489 0.69 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0815079-B1 METHOD FOR THE PREPARATION OF A N-ALKOXY-(TETRA- OR HEXAHYDRO)-PHTHALIMIDE AND METHOD FOR THE PREPARATION OF A N-ALKOXYAMINE DSM NV (NL) 2002-01-02 EP disclosed
US-5824804-A Method for the preparation of a N-alkoxy-(tetra-or hexahydro)-phthalimide and method for the preparation of a N-alkoxyamine DSM N.V. (NL) 1998-10-20 US disclosed
EP-0815079-A1 METHOD FOR THE PREPARATION OF A N-ALKOXY-(TETRA- OR HEXAHYDRO)-PHTHALIMIDE AND METHOD FOR THE PREPARATION OF A N-ALKOXYAMINE DSM N.V. (NL) 1998-01-07 EP disclosed
WO-1996030340-A1 METHOD FOR THE PREPARATION OF A N-ALKOXY-(TETRA- OR HEXAHYDRO)-PHTHALIMIDE AND METHOD FOR THE PREPARATION OF A N-ALKOXYAMINE DSM N.V. (NL) 1996-10-03 WO disclosed