Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709211 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL5711727 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL10967255 | 0.77 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8406973 | 0.75 | — | — | |
| SCHEMBL8149050 | 0.74 | CYP2D6 (0.30) | — | |
| SCHEMBL15184112 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPT | |
| SCHEMBL8149048 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPT | |
| SCHEMBL7515119 | 0.73 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8163464 | 0.73 | ALPL (0.33) | ALDH1A1TSHRMAPTPOLB | |
| SCHEMBL5448489 | 0.73 | ALDH1A1 (0.32) | ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592307-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2009-09-22 | — | — | US | claimed |
| US-20080279922-A1 | Releasable linkage and compositions containing same | ALZA CORPORATION | 2008-11-13 | — | — | US | claimed |
| US-20080152702-A1 | Releasable linkage and compositions containing same | ZALIPSKY SAMUEL | 2008-06-26 | — | — | US | claimed |
| EP-1880736-A1 | Releasable linkage and composition containing same | Alza Corporation (US) | 2008-01-23 | — | — | EP | claimed |
| EP-1701744-A2 | THIOL-CLEAVABLE LINKAGE BETWEEN POLYMER AND LIGAND | ALZA CORPORATION (US) | 2006-09-20 | — | — | EP | claimed |
| WO-2005053749-A2 | THIOL-CLEAVABLE LINKAGE BETWEEN POLYMER AND LIGAND | ALZA CORPORATION (US) | 2005-06-16 | — | — | WO | claimed |
| US-6849270-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2005-02-01 | — | — | US | claimed |
| US-20040213759-A1 | Releasable linkage and compositions containing same | ALZA CORPORATION | 2004-10-28 | — | — | US | claimed |
| US-20030211079-A1 | Releasable linkage and compositions containing same | ALZA CORPORATION | 2003-11-13 | — | — | US | claimed |
| JP-2002542386-A | — | — | 2002-12-10 | — | — | JP | claimed |
| US-20020128195-A1 | Releasable linkage and compositions containing same | ALZA CORPORATION | 2002-09-12 | — | — | US | claimed |
| US-6342244-B1 | HYDROPHILIC POLYMER COVALENTLY YET REVERSIBLY LINKED TO A AMINE-CONTAINING LIGAND THROUGH A DITHIOBENZYL LINKAGE; MODIFICATION OF VARIOUS SUBSTRATES, SUCH AS POLYPEPTIDES, DRUGS AND LIPOSOMES; UPON CLEAVAGE OF THE LINKAGE, THE LIGAND | ALZA CORPORATION | 2002-01-29 | — | — | US | claimed |
| EP-1173221-A2 | RELEASABLE LINKAGE AND COMPOSITIONS CONTAINING SAME | Alza Corporation (US) | 2002-01-23 | — | — | EP | claimed |
| WO-2000064483-A2 | RELEASABLE LINKAGE AND COMPOSITIONS CONTAINING SAME | ALZA CORPORATION (US) | 2000-11-02 | — | — | WO | claimed |
| US-20100009908-A1 | Galectin 9-Polymer Conjugates | GALPHARMA CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-7608687-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2009-10-27 | — | — | US | disclosed |
| US-7592307-B2 | Releasable linkage and compositions containing same | ALZA CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| US-5324844-A | From phosgenated polyether and n-hydroxyimide; for covalent attachment to proteins to produce hydrolysis-resistant carbamate group | ENZON, INC. (US) | 1994-06-28 | — | — | US | disclosed |
| US-5122614-A | Stable, hydrolysis resistant linkages | ENZON, INC. (US) | 1992-06-16 | — | — | US | disclosed |
| EP-0023371-A1 | Underwater coating composition | ASTRAL Société de Peintures et Vernis (FR) | 1981-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030211079-A1 | Releasable linkage and compositions containing same | CD44, ILK, CD69 | ALDH1A1 1574/4885TDP1 378/4885CYP3A4 3975/4885 |
| US-20020128195-A1 | Releasable linkage and compositions containing same | CD44, ILK, CD69 | ALDH1A1 1574/4885TDP1 378/4885CYP3A4 3975/4885 |
| US-20080279922-A1 | Releasable linkage and compositions containing same | CD44, SHMT1, HCAR1 | ALDH1A1 718/4885TDP1 603/4885CYP3A4 1171/4885 |
| US-20080152702-A1 | Releasable linkage and compositions containing same | CD44, ILK, CD69 | ALDH1A1 1574/4885TDP1 378/4885CYP3A4 3975/4885 |
| US-20040213759-A1 | Releasable linkage and compositions containing same | CD44, SHMT1, HCAR1 | ALDH1A1 718/4885TDP1 603/4885CYP3A4 1171/4885 |
| US-20100009908-A1 | Galectin 9-Polymer Conjugates | LGALS9, LGALS1, LGALS2 | ALDH1A1 3059/4885TDP1 2243/4885CYP3A4 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.