Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771507 | 0.84 | BACE1 (0.44) | LMNAPTGS1L3MBTL1POLBKMT2A | |
| SCHEMBL7976000 | 0.80 | HTT (0.50) | LMNAPTGS1KMT2A | |
| SCHEMBL7451566 | 0.78 | HTT (0.58) | POLBKMT2A | |
| SCHEMBL9701036 | 0.77 | HTT (0.44) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL10562880 | 0.77 | CYP3A4 (0.45) | LMNAL3MBTL1ALDH1A1MEN1POLB | |
| SCHEMBL9518855 | 0.76 | LMNA (0.46) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL11274902 | 0.76 | ALDH1A1 (0.55) | LMNAADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL7300749 | 0.75 | TRPA1 (0.41) | CYP2D6MAOAALDH1A1MEN1POLB | |
| SCHEMBL7277789 | 0.75 | TRPA1 (0.41) | CYP2D6MAOAALDH1A1MEN1POLB | |
| SCHEMBL9708802 | 0.75 | TRPA1 (0.41) | CYP2D6MAOAALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175385-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Pharmacor Inc. (CA) | 2002-01-30 | — | — | EP | disclosed |
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |
| WO-2000066524-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PHARMACOR INC. (CA) | 2000-11-09 | — | — | WO | disclosed |