Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523145 | 0.85 | EPHX2 (0.51) | LMNAEPHX1EPHX2TSHRGAA | |
| SCHEMBL7528869 | 0.81 | MEN1 (0.48) | LMNAEPHX1EPHX2TSHRGAA | |
| SCHEMBL7519932 | 0.79 | EPHX2 (0.49) | LMNAEPHX1EPHX2GAASMN1; SMN2 | |
| SCHEMBL9202790 | 0.76 | EPHX1 (0.78) | LMNAEPHX1EPHX2KDM4EGAA | |
| SCHEMBL7515777 | 0.76 | EPHX1 (0.45) | LMNAEPHX1EPHX2KDM4ETSHR | |
| SCHEMBL7554903 | 0.76 | RAB9A (0.42) | LMNAEPHX1EPHX2KDM4ETSHR | |
| SCHEMBL7528507 | 0.75 | SMN1; SMN2 (0.67) | EPHX1EPHX2KDM4ETSHRGAA | |
| Hydrochloric Acid SCHEMBL5119147 | 0.75 | EPHX1 (0.75) | LMNAEPHX1EPHX2KDM4EGAA | |
| SCHEMBL27985529 | 0.73 | EPHX1 (0.61) | LMNAEPHX1EPHX2GAASMN1; SMN2 | |
| SCHEMBL7523868 | 0.73 | LMNA (0.38) | LMNAEPHX1EPHX2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |