Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 9/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523871 | 0.82 | LMNA (0.35) | LMNARAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL7518027 | 0.79 | RAB9A (0.45) | LMNARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL27524607 | 0.76 | RAB9A (0.44) | LMNARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL7515770 | 0.73 | LMNA (0.49) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7554903 | 0.73 | RAB9A (0.42) | LMNAP2RX3RAB9ANPC1ALDH1A1 | |
| SCHEMBL7525013 | 0.72 | EPHX1 (0.61) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7522213 | 0.72 | RAB9A (0.45) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7515054 | 0.72 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL7524987 | 0.71 | PPIA (0.46) | LMNARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7517906 | 0.70 | KMT2A (0.38) | RAB9ANPC1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |