Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | GAA | P10253 | 9/20 | 0.55 |
| ▸ | THRB | P10828 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | BLM | P54132 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | PLEC | Q15149 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983424 | 0.85 | MAOA (0.51) | MAPTGAATHRBL3MBTL1MEN1 | |
| SCHEMBL563869 | 0.84 | HDAC3 (0.47) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL31438448 | 0.84 | HDAC3 (0.47) | MAPTGAAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL2989034 | 0.83 | MAOA (0.50) | MAPTGAATHRBL3MBTL1MEN1 | |
| SCHEMBL10781073 | 0.81 | MAPT (0.73) | MAPTGAATHRBL3MBTL1MEN1 | |
| SCHEMBL7519446 | 0.81 | MAPT (0.50) | MAPTMEN1KMT2AHPGDEGFR | |
| SCHEMBL6272046 | 0.79 | EGFR (0.54) | MAPTGAATHRBL3MBTL1MEN1 | |
| SCHEMBL6340604 | 0.79 | EGFR (0.54) | MAPTGAATHRBL3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL6269529 | 0.77 | EGFR (0.53) | MAPTGAATHRBL3MBTL1MEN1 | |
| SCHEMBL13971041 | 0.77 | ALDH1A1 (0.47) | MAPTGAATHRBL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032262-A1 | 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds | ZHANG JINFANG (US) | 2002-03-14 | — | — | US | disclosed |