SCHEMBL751609

SCHEMBL751609

N[C@@H](Cc1ccc(O)cc1F)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.57
ALOX15 P16050 3/20 0.57
HSD17B10 Q99714 3/20 0.57
KDM4E B2RXH2 3/20 0.57
CYP3A4 P08684 2/20 0.57
NFKB1 P19838 2/20 0.57
ALDH1A1 P00352 2/20 0.57
LMNA P02545 2/20 0.57
MAPT P10636 2/20 0.57
BLM P54132 2/20 0.57
PMP22 Q01453 2/20 0.57
KMT2A Q03164 2/20 0.57
NPSR1 Q6W5P4 2/20 0.57
HIF1A Q16665 2/20 0.57
RECQL P46063 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
PKM P14618 2/20 0.57
RGS12 O14924 1/20 0.57
CYP2C9 P11712 1/20 0.57
CASP1 P29466 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12375142 1.00 USP2 (0.57) USP2ALOX15HSD17B10KDM4ECYP3A4
SCHEMBL1577675 1.00 USP2 (0.57) USP2ALOX15HSD17B10KDM4ECYP3A4
Bromide SCHEMBL865648 0.98 USP2 (0.56) USP2ALOX15HSD17B10KDM4ECYP3A4
Bromide SCHEMBL865649 0.98 USP2 (0.56) USP2ALOX15HSD17B10KDM4ECYP3A4
SCHEMBL26664897 0.93 USP2 (0.50) USP2ALOX15HSD17B10KDM4ECYP3A4
SCHEMBL15130503 0.87 ALOX15 (0.57) USP2ALOX15HSD17B10KDM4ECYP3A4
SCHEMBL322219 0.87 ALOX15 (0.57) USP2ALOX15HSD17B10KDM4ECYP3A4
SCHEMBL5981375 0.87 ALOX15 (0.57) USP2ALOX15HSD17B10KDM4ECYP3A4
SCHEMBL15130505 0.87 ALOX15 (0.57) USP2ALOX15HSD17B10KDM4ECYP3A4
SCHEMBL19501942 0.87 ALOX15 (0.57) USP2ALOX15HSD17B10KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094701-A TLR3 binding bicyclic peptide ligands 2026-05-26 CN claimed
WO-2025046244-A1 TLR3 BINDING BICYCLIC PEPTIDE LIGANDS BICYCLETX LIMITED (GB) 2025-03-06 WO claimed
EP-4274838-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LTD (GB) 2024-09-25 EP claimed
US-20240108738-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LIMITED (GB) 2024-04-04 US claimed
CN-117529489-A Bicyclic peptide ligands specific for NK cells 拜斯科技术开发有限公司 2024-02-06 CN claimed
EP-4274838-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BicycleTx Limited (GB) 2023-11-15 EP claimed
WO-2022148974-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LIMITED (GB) 2022-07-14 WO claimed
US-11053249-B2 Proteasome inhibiting β-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders PHILIPPE YVES-REMY SIMON (FR) 2021-07-06 US claimed
US-20200216455-A1 Proteasome Inhibiting Beta-Lactam Produrgs Useful for the Treatment of Cancer and Nurodegenerative Disorders VITA API (FR) 2020-07-09 US claimed
CN-110885358-A Vaccine for preventing tumor recurrence and metastasis and application method thereof 浙江爱睦世医学科技有限公司 2020-03-17 CN claimed
CN-110857314-A Active polypeptide, polypeptide derivative, composition and using method thereof 许洋 2020-03-03 CN claimed
WO-2018115497-A1 PROTEASOME INHIBITING ß-LACTAM PRODRUGS USEFUL FOR THE TREATMENT OF CANCER AND NEURODEGENERATIVE DISORDERS VITA API (FR) 2018-06-28 WO claimed
EP-3339291-A1 PROTEASOME INHIBITING SS-LACTAM PRODRUGS USEFUL FOR THE TREATMENT OF CANCER AND NEURODEGENERATIVE DISORDERS VITA API (FR) 2018-06-27 EP claimed
EP-2876165-A1 Improved method for producing modifed target polypeptides ACIB GmbH (AT) 2015-05-27 EP claimed
US-20050137421-A1 Method for making fluorine labled L-Dopa CTI PET SYSTEMS, INC. 2005-06-23 US claimed
CN-122094701-A TLR3 binding bicyclic peptide ligands 2026-05-26 CN disclosed
CN-119120437-B Tyrosine phenol lyase mutant and application thereof in synthesis of tyrosine derivatives 浙江工业大学 2025-10-28 CN disclosed
WO-2003018553-A1 ORAL ANTIDIABETIC AGENTS WARNER-LAMBERT COMPANY LLC (US) 2003-03-06 WO disclosed
US-5254726-A Reacting aromatic nitroaldehydes having protected hydroxyl groups with labeled fluoride ion THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF ENERGY (US) 1993-10-19 US disclosed
US-4925651-A TUMOR DIAGNOSIS KERNFORSCHUNGSANLAGE JUELICH GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108738-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS PBK, KLRK1, MICA USP2 4659/4885ALOX15 1994/4885HSD17B10 4416/4885
US-11053249-B2 Proteasome inhibiting β-lactam prodrugs useful for the treatment of cancer and neurodegenerative disorders PSMB5, PSMB1, PSMB11 USP2 102/4885ALOX15 2434/4885HSD17B10 1893/4885
US-20050137421-A1 Method for making fluorine labled L-Dopa MAOB, DBH, MAOA USP2 3634/4885ALOX15 129/4885HSD17B10 1077/4885
US-20200216455-A1 Proteasome Inhibiting Beta-Lactam Produrgs Useful for the Treatment of Cancer and Nurodegenerative Disorders PSMB5, PSMB1, PSMB11 USP2 129/4885ALOX15 2878/4885HSD17B10 1810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.