Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15130503 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL5981375 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL29897601 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL15130505 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL19501942 | 1.00 | ALOX15 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6469073 | 0.98 | USP2 (0.56) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6469069 | 0.98 | USP2 (0.56) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL12375142 | 0.87 | USP2 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL1577675 | 0.87 | USP2 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 | |
| SCHEMBL751609 | 0.87 | USP2 (0.57) | ALOX15HSD17B10USP2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | THE GENERAL HOSPITAL CORPORATION | 2017-05-04 | — | — | US | claimed |
| US-10259800-B2 | Method of fluorination using iodonium ylides | THE GENERAL HOSPITAL CORPORATION (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | THE GENERAL HOSPITAL CORPORATION | 2017-05-04 | — | — | US | disclosed |
| US-20130190529-A1 | Fluorine Radiolabelling Process | ISIS INNOVATION LIMITED (GB) | 2013-07-25 | — | — | US | disclosed |
| EP-2590910-A2 | FLUORINE RADIOLABELLING PROCESS | Isis Innovation Limited (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004567-A2 | FLUORINE RADIOLABELLING PROCESS | ISIS INNOVATION LIMITED (GB) | 2012-01-12 | — | — | WO | disclosed |
| WO-2009097144-A1 | MOLECULAR PROBES FOR PET-IMAGING OF DOPAMINE NEUROTRANSMISSION AND NEUROENDOCRINE PROCESSES IN VIVO | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-08-06 | — | — | WO | disclosed |
| EP-1979372-A2 | METHODS OF LABELING TRANSIENTLY EXPRESSED PROTEINS IN LARGE-SCALE EUKARYOTIC CELL CULTURES | Wyeth (US) | 2008-10-15 | — | — | EP | disclosed |
| EP-1658099-B1 | COMPOUNDS AND KITS FOR PREPARING IMAGING AGENTS AND METHODS OF IMAGING | GEN ELECTRIC (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2008060307-A2 | METHODS OF LABELING TRANSIENTLY EXPRESSED PROTEINS IN LARGE-SCALE EUKARYOTIC CELL CULTURES | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |
| US-20070161047-A1 | Methods of labeling transiently expressed proteins in large-scale eukaryotic cell cultures | WYETH | 2007-07-12 | — | — | US | disclosed |
| US-7115766-B2 | Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORP. (US) | 2006-10-03 | — | — | US | disclosed |
| EP-1658099-A1 | COMPOUNDS AND KITS FOR PREPARING IMAGING AGENTS AND METHODS OF IMAGING | General Electric Company (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005023317-A1 | COMPOUNDS AND KITS FOR PREPARING IMAGING AGENTS AND METHODS OF IMAGING | GENERAL ELECTRIC COMPANY (US) | 2005-03-17 | — | — | WO | disclosed |
| US-20050049487-A1 | Compounds and kits for preparing imaging agents and methods of imaging | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | disclosed |
| US-20040034246-A1 | Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-19 | — | — | US | disclosed |
| WO-2002044144-A2 | NUCLEOPHILIC APPROACH FOR PREPARING RADIOLABELED IMAGING AGENTS AND ASSOCIATED COMPOUNDS | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2002-06-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | FLI1, ABL1, PFAS | ALOX15 2398/4885HSD17B10 2666/4885USP2 2636/4885 |
| US-20040034246-A1 | Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds | SNCA, PARK7, SAMHD1 | ALOX15 3001/4885HSD17B10 3891/4885USP2 2339/4885 |
| US-20130190529-A1 | Fluorine Radiolabelling Process | ESRRG, NR5A2, RXFP4 | ALOX15 2478/4885HSD17B10 956/4885USP2 2496/4885 |
| US-10259800-B2 | Method of fluorination using iodonium ylides | FLI1, ABL1, PFAS | ALOX15 2398/4885HSD17B10 2666/4885USP2 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.