Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | AHR | P35869 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349442 | 0.76 | APEX1 (0.53) | ALDH1A1AHRTSHRHSD17B10APEX1 | |
| SCHEMBL10872330 | 0.76 | ALDH1A1 (0.53) | ALDH1A1AHRTSHRHSD17B10HPGD | |
| SCHEMBL6660944 | 0.76 | APEX1 (0.60) | ALDH1A1AHRTSHRAPEX1CYP3A4 | |
| SCHEMBL358001 | 0.76 | ALDH1A1 (1.00) | ALDH1A1AHRTSHRHSD17B10HPGD | |
| SCHEMBL23327014 | 0.74 | TSHR (0.41) | ALDH1A1AHRTSHRHSD17B10HPGD | |
| SCHEMBL18686817 | 0.74 | ALDH1A1 (0.45) | ALDH1A1AHRTSHRHSD17B10HPGD | |
| SCHEMBL28667897 | 0.74 | TDP1 (0.41) | AHRTSHRAPEX1CYP3A4TDP1 | |
| SCHEMBL6500390 | 0.74 | ALDH1A1 (0.61) | ALDH1A1AHRTSHRHSD17B10HPGD | |
| SCHEMBL30007490 | 0.74 | TSHR (0.41) | ALDH1A1AHRTSHRHSD17B10HPGD | |
| SCHEMBL30293826 | 0.74 | ALDH1A1 (0.61) | ALDH1A1AHRTSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020007024-A1 | Contacting ethylene and/or ethylene and one other olefin under polymerization conditions with a Ziegler-Natta type catalyst, a halogenated hydrocarbon, a co-catalyst | WESTLAKE LONGVIEW CORPORATION | 2002-01-17 | — | — | US | disclosed |