SCHEMBL358001

SCHEMBL358001

Clc1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
AHR P35869 8/20 0.71
TSHR P16473 6/20 0.61
HSD17B10 Q99714 5/20 0.61
HPGD P15428 4/20 0.61
CYP3A4 P08684 4/20 0.53
CRHBP P24387 1/20 0.53
CRHR2 Q13324 1/20 0.53
RECQL P46063 1/20 0.53
CASP1 P29466 1/20 0.44
TP53 P04637 1/20 0.44
CYP1B1 Q16678 1/20 0.43
HSP90AA1 P07900 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560391 0.93 ALDH1A1 (0.86) ALDH1A1AHRTSHRHSD17B10HPGD
Methoxymethane SCHEMBL28100007 0.87 ALDH1A1 (0.75) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL8165912 0.87 ALDH1A1 (0.75) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4459925 0.84 AHR (1.00) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL27835679 0.84 ALDH1A1 (0.71) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL2930780 0.82 ALDH1A1 (0.69) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL28845466 0.80 ALDH1A1 (0.63) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4453256 0.80 AHR (0.64) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL463584 0.79 AHR (0.65) ALDH1A1AHRTSHRHSD17B10HPGD
SCHEMBL4456478 0.79 ALDH1A1 (0.65) ALDH1A1AHRTSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
US-12258448-B2 Method of making a biphenol dianhydride composition, method for purification of a biphenol dianhydride composition, and poly (etherimides) derived from the biphenol dianhydride SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-03-25 US claimed
CN-119657120-A Hydrodechlorination catalyst and preparation method thereof 江苏扬农化工集团有限公司 2025-03-21 CN claimed
CN-119633844-A Selective hydrogenation dechlorination catalyst for chlorinated organic compounds and preparation method thereof 江苏扬农化工集团有限公司 2025-03-18 CN claimed
CN-119565645-A Continuous hydrogenation dechlorination catalyst and preparation method thereof 江苏扬农化工集团有限公司 2025-03-07 CN claimed
CN-114002351-B Gas chromatography-mass spectrometry detection method for simultaneously detecting tetrachlorobenzene and pentachlorobenzene in chlorothalonil 江苏新河农用化工有限公司 2024-12-13 CN claimed
CN-117603033-A Preparation method of fluxapyroxad hydroxylamine intermediate 1- (2, 4, 6-trichlorophenyl) -propyl-2-ketone 山东京博农化科技股份有限公司 2024-02-27 CN claimed
CN-113956123-B Preparation method and application of 2-alkylanthracene 天津大学 2023-11-17 CN claimed
CN-112710760-B Method for determining chlorine organic pollutants in textile solid waste through multi-method combination 中华人民共和国乌鲁木齐海关 2022-11-25 CN claimed
CN-112710761-B Method for determining chlorine organic pollutants in textile raw material solid waste 中华人民共和国乌鲁木齐海关 2022-06-24 CN claimed
CN-104849385-B Gas chromatographic mass spectrometry determination method for chlorobenzene compounds 惠州市食品药品检验所 2017-01-11 CN claimed
CN-104849385-A Gas chromatographic mass spectrometry determination method for chlorobenzene compounds HUIZHOU INST FOR FOOD AND DRUG CONTROL 2015-08-19 CN claimed
CN-104741117-A Method and catalyst for preparing benzene and cyclohexane by catalytically hydrogenating liquid phase of aryl chloride NINGBO INST MATERIALS TECHNOLOGY & ENG CAS 2015-07-01 CN claimed
CN-103399113-B Solid phase membrane extraction-gas chromatography detection method for chlorobenzene compounds in water body ZHEJIANG PROV. INST. OF MARINE PRODUCTS (CN) 2014-10-15 CN claimed
CN-102788861-B Method for catching and detecting static headspace gas chromatography electrons of eleven chlorobenzene compounds in water MARINE FISHERIES RES INST ZHEJIANG 2014-04-16 CN claimed
CN-103399113-A Solid phase membrane extraction-gas chromatography detection method for chlorobenzene compounds in water body MARINE FISHERIES RES INST ZHEJIANG 2013-11-20 CN claimed
US-20130105387-A1 TREATMENT FOR DEPOLLUTING WATER CONTAMINATED BY MICRO POLLUTANTS AND/OR EMERGENT POLLUTANTS, NOTABLY BY ORGANOCHLORINATED COMPOUNDS RHODIA OPERATIONS (FR) 2013-05-02 US claimed
CN-102947230-A Decontamination treatment of water contaminated by emergent pollutants and/or micropollutants, especially by organochlorine compounds PHYTORESTORE 2013-02-27 CN claimed
CN-102875809-A Production method of polyphenylene sulphide resin specially used for foam material HUATONG SICHUAN RES CT FOR SPECIAL ENGINEERING PLASTICS 2013-01-16 CN claimed
CN-102788861-A Method for catching and detecting static headspace gas chromatography electrons of eleven chlorobenzene compounds in water MARINE FISHERIES RES INST ZHEJIANG 2012-11-21 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12258448-B2 Method of making a biphenol dianhydride composition, method for purification of a biphenol dianhydride composition, and poly (etherimides) derived from the biphenol dianhydride CA3, FHIT, PPIP5K2 ALDH1A1 4591/4885AHR 532/4885TSHR 2281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.