Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334659 | 0.87 | CYP4F2 (0.46) | CYP4F2CYP4A11HPGDP2RX7KMT2A | |
| SCHEMBL7556199 | 0.80 | P2RX7 (0.62) | P2RX7GAA | |
| SCHEMBL5142841 | 0.78 | NPC1 (0.44) | NPC1RAB9AP2RX7KMT2AMEN1 | |
| SCHEMBL7667287 | 0.75 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL5336406 | 0.74 | PPARA (0.46) | P2RX7KMT2AMEN1LMNA | |
| SCHEMBL6485285 | 0.74 | P2RX7 (0.53) | HPGDP2RX7KMT2AMEN1LMNA | |
| SCHEMBL7552476 | 0.73 | HPGD (0.54) | HPGDP2RX7CYP1A2KMT2AMEN1 | |
| SCHEMBL7555910 | 0.73 | POLB (0.43) | RAB9AHPGDKMT2AMEN1HDAC6 | |
| SCHEMBL4116624 | 0.72 | P2RX7 (0.64) | P2RX7KMT2AMEN1LMNA | |
| SCHEMBL7077870 | 0.72 | P2RX7 (0.54) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171432-A1 | ADAMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061569-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |