Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.44 |
| ▸ | PAICS | P22234 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951445 | 0.89 | P2RX7 (0.64) | P2RX7CHRM3GAAPAICS | |
| SCHEMBL7661977 | 0.87 | P2RX7 (0.61) | P2RX7CHRM3GAACHRM1 | |
| SCHEMBL7516797 | 0.80 | CYP4F2 (0.44) | P2RX7GAA | |
| SCHEMBL7660243 | 0.79 | P2RX7 (0.82) | P2RX7CHRM3 | |
| SCHEMBL7663299 | 0.76 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7657585 | 0.75 | P2RX7 (0.93) | P2RX7 | |
| SCHEMBL7559952 | 0.73 | P2RX7 (0.61) | P2RX7CHRM3CYP2D6HTR2A | |
| SCHEMBL5142841 | 0.71 | NPC1 (0.44) | P2RX7 | |
| SCHEMBL7553515 | 0.71 | P2RX7 (0.58) | P2RX7CHRM3CYP2D6HTR2A | |
| SCHEMBL7555457 | 0.70 | P2RX7 (0.47) | P2RX7CHRM3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171432-A1 | ADAMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061569-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |