Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513482 | 0.95 | CA12 (0.41) | CA2CA12CA9RAB9ASMN1; SMN2 | |
| SCHEMBL7509603 | 0.95 | CA1 (0.41) | CA2SERPINE1CA1MMP1MMP2 | |
| SCHEMBL7509594 | 0.95 | CA1 (0.41) | CA2SERPINE1CA1MMP1MMP2 | |
| SCHEMBL7518577 | 0.95 | CA1 (0.41) | CA2SERPINE1CA1MMP1MMP2 | |
| SCHEMBL14080566 | 0.92 | KMT2A (0.41) | CA2SMN1; SMN2SERPINE1CA1MMP1 | |
| SCHEMBL14080613 | 0.92 | KMT2A (0.41) | CA2SMN1; SMN2SERPINE1CA1MMP1 | |
| SCHEMBL14080627 | 0.92 | KMT2A (0.41) | CA2SMN1; SMN2SERPINE1CA1MMP1 | |
| SCHEMBL14080720 | 0.91 | CNR2 (0.41) | CA2SMN1; SMN2SERPINE1CA1MMP1 | |
| SCHEMBL7523657 | 0.88 | PKM (0.40) | CA2SMN1; SMN2SERPINE1CA1MMP1 | |
| SCHEMBL14080753 | 0.87 | F2 (0.37) | CA2SMN1; SMN2SERPINE1CA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2002-04-18 | — | — | US | disclosed |
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | SRM, SLC7A1, CATSPER1 | CA2 984/4885CA12 3973/4885CA9 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.