Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479788 | 0.84 | MTNR1A (0.72) | MTNR1ASMN1; SMN2 | |
| SCHEMBL7526482 | 0.79 | MTNR1A (0.85) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL7523790 | 0.74 | MTNR1A (0.86) | MTNR1AMTNR1BNR4A2CTNNB1WNT3A | |
| SCHEMBL7520035 | 0.71 | MTNR1A (1.00) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL7524387 | 0.70 | MTNR1A (1.00) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL7520038 | 0.68 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| SCHEMBL7517761 | 0.68 | MTNR1A (1.00) | MTNR1AMTNR1BCTNNB1WNT3ANPC1 | |
| SCHEMBL7520703 | 0.67 | MTNR1A (0.93) | MTNR1AMTNR1BCTNNB1WNT3A | |
| SCHEMBL7517881 | 0.67 | MTNR1A (0.50) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL13942638 | 0.65 | MTNR1A (0.48) | MTNR1AMTNR1BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |