SCHEMBL7518324

SCHEMBL7518324

BrC(Br)(Br)c1nc(-c2ccccc2)nc(C(Br)(Br)Br)n1.ClC(Cl)(Cl)c1nc(-c2ccccc2)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HTT P42858 2/20 0.41
ADORA2A P29274 2/20 0.41
ADORA1 P30542 2/20 0.41
POLB P06746 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ADORA2B P29275 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
MAPK1 P28482 1/20 0.38
LMNA P02545 2/20 0.38
CCNB2 O95067 1/20 0.36
CCNE2 O96020 1/20 0.36
CDK1 P06493 1/20 0.36
CDK4 P11802 1/20 0.36
CCNB1 P14635 1/20 0.36
CCNA2 P20248 1/20 0.36
CCND1 P24385 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4900598 0.92 MEN1 (0.47) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL80527 0.92 MEN1 (0.47) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL1043823 0.90 ADORA2A (0.48) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL125466 0.88 MEN1 (0.44) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL18344448 0.83 LMNA (0.41) MEN1KMT2AHTTADORA2AADORA1
Diphenylamine SCHEMBL391850 0.81 IDH2 (0.47) MEN1KMT2AHTTPOLBL3MBTL1
SCHEMBL8412982 0.81 NPC1 (0.38) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL3218601 0.80 MEN1 (0.38) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL5676700 0.80 MEN1 (0.38) MEN1KMT2AHTTADORA2AADORA1
SCHEMBL9079576 0.79 L3MBTL1 (0.64) MEN1KMT2AHTTADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020076642-A1 Antireflective composition SHIPLEY COMPANY, L.L.C. 2002-06-20 US disclosed