SCHEMBL7518374

SCHEMBL7518374

C=C(OP(=O)(OC)c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.41
LMNA P02545 1/20 0.41
CA2 P00918 3/20 0.41
CA4 P22748 2/20 0.41
CA5A P35218 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 3/20 0.39
ALOX15 P16050 1/20 0.39
CFTR P13569 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ESR1 P03372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7512310 0.80 LMNA (0.44) POLBLMNACA2TDP1MEN1
SCHEMBL7513602 0.78 ALDH1A1 (0.42) LMNACA2CA4CA5ATDP1
SCHEMBL499887 0.77 L3MBTL1 (0.56) POLBCA2CA4CA5ACA12
SCHEMBL28415907 0.75 CA12 (0.45) POLBLMNACA2CA4CA5A
SCHEMBL11499542 0.75 CA2 (0.39) LMNACA2CA4CA5ATDP1
SCHEMBL14116478 0.74 L3MBTL1 (0.48) POLBLMNACA2CA4CA5A
SCHEMBL3908206 0.74 SRC (0.45) POLBLMNACA2CA4CA5A
Hydrochloric Acid SCHEMBL27560556 0.73 L3MBTL1 (0.52) POLBCA2CA4CA5ACA12
SCHEMBL29196135 0.72 POLB (0.41) POLBLMNACA2CA4CA5A
SCHEMBL29196146 0.72 ALDH1A1 (0.42) POLBLMNACA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020016424-A1 Synthesizing polymers using phosphorous-containing addition-fragmentation chain transfer agents; molecular weight control AKRON, THE UNIVERSITY OF 2002-02-07 US claimed
WO-2000020465-A1 NOVEL CHAIN TRANSFER AGENTS THE UNIVERSITY OF AKRON (US) 2000-04-13 WO claimed
US-6399731-B2 SYNTHESIZING POLYMERS USING PHOSPHOROUS-CONTAINING ADDITION-FRAGMENTATION CHAIN TRANSFER AGENTS; MOLECULAR WEIGHT CONTROL THE UNIVERSITY OF AKRON 2002-06-04 US disclosed
US-20020016424-A1 Synthesizing polymers using phosphorous-containing addition-fragmentation chain transfer agents; molecular weight control AKRON, THE UNIVERSITY OF 2002-02-07 US disclosed
WO-2000020465-A1 NOVEL CHAIN TRANSFER AGENTS THE UNIVERSITY OF AKRON (US) 2000-04-13 WO disclosed