SCHEMBL751864

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754417	0.87	ALDH1A1 (0.36)	LIPGALDH1A1POLBGAAL3MBTL1
	SCHEMBL27777099	0.84	LIPG (0.43)	LIPGALDH1A1POLBGAAL3MBTL1
	SCHEMBL754971	0.84	LIPG (0.55)	LIPGALDH1A1POLBNPSR1HTT
	SCHEMBL753326	0.78	LIPG (0.46)	LIPGALDH1A1POLBNPSR1HTT
	SCHEMBL27777088	0.75	POLB (0.37)	LIPGALDH1A1POLBGAAL3MBTL1
	SCHEMBL753324	0.73	ALDH1A1 (0.42)	LIPGALDH1A1POLBGAAL3MBTL1
	SCHEMBL752064	0.72	POLB (0.41)	LIPGALDH1A1POLBNPSR1HTT
	SCHEMBL765090	0.70	ALDH1A1 (0.40)	LIPGALDH1A1POLBGAAL3MBTL1
	SCHEMBL753335	0.70	CNR2 (0.38)	ALDH1A1POLBNPSR1HTTLMNA
	SCHEMBL10290647	0.70	ALDH1A1 (0.38)	ALDH1A1POLBNPSR1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.