SCHEMBL754971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27777099	0.86	LIPG (0.43)	LIPGALDH1A1POLBNPSR1TP53
	SCHEMBL753326	0.86	LIPG (0.46)	LIPGALDH1A1POLBNPSR1TP53
	SCHEMBL751864	0.84	LIPG (0.42)	LIPGALDH1A1POLBNPSR1MEN1
	SCHEMBL753324	0.81	ALDH1A1 (0.42)	LIPGALDH1A1POLBNPSR1MEN1
	SCHEMBL765090	0.78	ALDH1A1 (0.40)	LIPGALDH1A1POLBNPSR1MEN1
	SCHEMBL752064	0.78	POLB (0.41)	LIPGALDH1A1POLBNPSR1CNR2
	SCHEMBL5519468	0.75	LIPG (0.88)	LIPGALDH1A1LIPCNPSR1TP53
	SCHEMBL754588	0.75	ALDH1A1 (0.39)	LIPGALDH1A1POLBTP53MEN1
	SCHEMBL27777088	0.74	POLB (0.37)	LIPGALDH1A1POLBNPSR1TP53
	SCHEMBL752899	0.73	LIPG (0.51)	LIPGALDH1A1POLBLIPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.