Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | REN | P00797 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 6/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163407 | 0.77 | CTSK (0.47) | CTSKRENCTSSCTSLCTSB | |
| SCHEMBL7412248 | 0.76 | CTSK (0.44) | CTSKRENCTSSCTSLCTSB | |
| SCHEMBL7565916 | 0.73 | CTSK (0.38) | CTSKRENCTSSCTSLCA5A | |
| SCHEMBL7160715 | 0.71 | LARS1 (0.44) | CTSK | |
| SCHEMBL7610538 | 0.69 | CTSK (0.56) | CTSKCTSSCTSLCTSBCA5A | |
| SCHEMBL27555854 | 0.69 | CTSK (0.56) | CTSKCTSSCTSLCTSBCA5A | |
| SCHEMBL7467714 | 0.69 | CTSK (0.46) | CTSKRENCTSSPSMB5CTSL | |
| SCHEMBL8418512 | 0.67 | REN (0.65) | CTSKRENCTSSCTSLCTSB | |
| SCHEMBL21885556 | 0.65 | CTSK (0.63) | CTSKRENCTSSCTSLCTSB | |
| SCHEMBL18154376 | 0.65 | CTSK (0.63) | CTSKRENCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |