Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163407 | 0.85 | CTSK (0.47) | CTSKCTSSRENCA5ACTSL | |
| SCHEMBL7412248 | 0.83 | CTSK (0.44) | CTSKCTSSRENCA5ABACE1 | |
| SCHEMBL7160715 | 0.80 | LARS1 (0.44) | CTSK | |
| SCHEMBL7610538 | 0.78 | CTSK (0.56) | CTSKCTSSCA5ACA1CTSL | |
| SCHEMBL7467714 | 0.74 | CTSK (0.46) | CTSKCTSSRENPSEN1PSEN2 | |
| SCHEMBL7518972 | 0.73 | CTSK (0.38) | CTSKCTSSRENCA5APSEN1 | |
| SCHEMBL27555854 | 0.69 | CTSK (0.56) | CTSKCTSSCA5ACA1CTSL | |
| SCHEMBL6618230 | 0.69 | CTSK (0.47) | CTSKCTSSRENPSEN1PSEN2 | |
| SCHEMBL6635507 | 0.67 | CTSK (0.46) | CTSKCTSSRENPSEN1PSEN2 | |
| SCHEMBL7240364 | 0.67 | CTSK (0.53) | CTSKCTSSCA5ACA1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020077455-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2002-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077455-A1 | Protease inhibitors | CTSK, CTSZ, CTSG | CTSK 1/4885CTSS 8/4885REN 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.